H Trent Spencer: search on Z-Library

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1

Mediterranean grassland soil C–N compound turnover is dependent on rainfall and depth, and is mediated by genomically divergent microorganisms

Diamond, Spencer, Andeer, Peter F., Li, Zhou, Crits-Christoph, Alexander, Burstein, David, Anantharaman, Karthik, Lane, Katherine R., Thomas, Brian C., Pan, Chongle, Northen, Trent R., Banfield, Jilli

Journal:

Nature Microbiology

Year:

2019

Language:

english

File:

PDF, 2.96 MB

english, 2019

2

Mediterranean grassland soil C–N compound turnover is dependent on rainfall and depth, and is mediated by genomically divergent microorganisms

Diamond, Spencer, Andeer, Peter F., Li, Zhou, Crits-Christoph, Alexander, Burstein, David, Anantharaman, Karthik, Lane, Katherine R., Thomas, Brian C., Pan, Chongle, Northen, Trent R., Banfield, Jilli

Journal:

Nature Microbiology

Year:

2019

File:

PDF, 2.96 MB

2019

3

Functional aspects of factor VIII expression after transplantation of genetically-modified hematopoietic stem cells for hemophilia A

Lucienne M. Ide, Neal N. Iwakoshi, Bagirath Gangadharan, Shawn Jobe, Robert Moot, David McCarty, Christopher B. Doering, H. Trent Spencer

Journal:

The Journal of Gene Medicine

Year:

2010

Language:

english

File:

PDF, 475 KB

english, 2010

4

Treatment of a Solid Tumor Using Engineered Drug-Resistant Immunocompetent Cells and Cytotoxic Chemotherapy

Dasgupta, Anindya, Shields, Jordan E., Spencer, H. Trent

Journal:

Human Gene Therapy

Year:

2012

Language:

english

File:

PDF, 516 KB

english, 2012

5

Enhancing the pharmaceutical properties of protein drugs by ancestral sequence reconstruction

Zakas, Philip M, Brown, Harrison C, Knight, Kristopher, Meeks, Shannon L, Spencer, H Trent, Gaucher, Eric A, Doering, Christopher B

Journal:

Nature Biotechnology

Year:

2016

Language:

english

File:

PDF, 516 KB

english, 2016

6

Packing and deploying Soft Origami to and from cylindrical volumes with application to automotive airbags

Bruton, Jared T., Nelson, Todd G., Zimmerman, Trent K., Fernelius, Janette D., Magleby, Spencer P., Howell, Larry L.

Journal:

Royal Society Open Science

Year:

2016

Language:

english

File:

PDF, 1.39 MB

english, 2016

7

Target Cell Directed Bioengineering Approaches for Gene Therapy of Hemophilia A

Brown, Harrison C., Zakas, Philip M., George, Stephan N., Parker, Ernest T., Spencer, H Trent, Doering, Christopher B.

Journal:

Molecular Therapy — Methods & Clinical Development

Year:

2018

Language:

english

File:

PDF, 3.46 MB

english, 2018

8

Combating Vaccine Hesitancy with Vaccine-Preventable Disease Familiarization: An Interview and Curriculum Intervention for College Students

Johnson, Deborah K., Mello, Emily J., Walker, Trent D., Hood, Spencer J., Jensen, Jamie L., Poole, Brian D.

Journal:

Year:

2019

File:

PDF, 1.19 MB

2019

9

Characterization of a molecular switch system that regulates gene expression in mammalian cells through a small molecule

Jennifer L Taylor, Priyanka Rohatgi, H Trent Spencer, Donald F Doyle, Bahareh Azizi

Journal:

BMC Biotechnology

Year:

2010

Language:

english

File:

PDF, 3.39 MB

english, 2010

10

Engineered resistance to camptothecin and antifolates by retroviral coexpression of tyrosyl DNA phosphodiesterase-I and thymidylate synthase

MichaelC. Nivens, Takita Felder, AmandaH. Galloway, MariaMarjoretteO. Pena, JefferyJ. Pouliot, H.Trent Spencer

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2004

Language:

english

File:

PDF, 344 KB

english, 2004

11

Enforced expression of cytosolic 5′-nucleotidase I confers resistance to nucleoside analogues in vitro but systemic chemotherapy toxicity precludes in vivo selection

Tasha Gray, Erin L. Morrey, Bagirath Gangadharan, Takita F. Sumter, Jozef Spychala, David R. Archer, H. Trent Spencer

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2006

Language:

english

File:

PDF, 478 KB

english, 2006

12

Ureteric embolization: an alternative treatment strategy for urinary fistulae complicating advanced pelvic malignancy

Vaithianathan Natarajan, Nigel R. Boucher, Pieter Meiring, Paul Spencer, Bo T. Parys, Neil E. Oakley, for the Stent (Society for Endourology in North Trent) group

Journal:

BJU International

Year:

2007

Language:

english

File:

PDF, 176 KB

english, 2007

13

Presynaptic spike broadening reduces junctional potential amplitude

Spencer, Andrew N., Przysiezniak, Jan, Acosta-Urquidi, Juan, Basarsky, Trent A.

Journal:

Year:

1989

File:

PDF, 341 KB

1989

14

Delivery of nucleic acid therapeutics by genetically engineered hematopoietic stem cells

Christopher B. Doering, David Archer, H. Trent Spencer

Journal:

Advanced Drug Delivery Reviews

Year:

2010

Language:

english

File:

PDF, 332 KB

english, 2010

15

Phenotypic correction of hemophilia A in sheep by postnatal intraperitoneal transplantation of FVIII-expressing MSC

Christopher D. Porada, Chad Sanada, Chung-Jung Kuo, Evan Colletti, Walter Mandeville, John Hasenau, Esmail D. Zanjani, Robert Moot, Christopher Doering, H. Trent Spencer, Graça Almeida-Porada

Journal:

Experimental Hematology

Year:

2011

Language:

english

File:

PDF, 1.69 MB

english, 2011

16

Differences in natural ligand and fluoropyrimidine binding to human thymidylate synthase identified by transient-state spectroscopic and continuous variation methods

Takita Felder, R.Bruce Dunlap, Daniel Dix, Trent Spencer

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

2002

Language:

english

File:

PDF, 225 KB

english, 2002

17

Season of birth in multiple sclerosis

D. I. Templer, N. H. Trent, D. A. Spencer, A. Trent, M. D. Corgiat, P. B. Mortensen, M. Gorton

Journal:

Acta Neurologica Scandinavica

Year:

1992

Language:

english

File:

PDF, 221 KB

english, 1992

18

Kinetic Studies on Drug-Resistant Variants of Escherichia coli Thymidylate Synthase: Functional Effects of Amino Acid Substitutions at Residue 4

Elahe Mahdavian, H.Trent Spencer, R.Bruce Dunlap

Journal:

Archives of Biochemistry and Biophysics

Year:

1999

Language:

english

File:

PDF, 232 KB

english, 1999

19

Retroviral Coexpression of Thymidylate Synthase and Dihydrofolate Reductase Confers Fluoropyrimidine and Antifolate Resistance

Corinne R. Fantz, David Shaw, John G. Moore, H.Trent Spencer

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 180 KB

english, 1998

20

Highly efficient transduction of repopulating bone marrow cells using rapidly concentrated polymer-complexed retrovirus

Douglas W. McMillin, Natalia Landázuri, Bagirath Gangadharan, Becker Hewes, David R. Archer, H. Trent Spencer, Joseph M. Le Doux

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 495 KB

english, 2005

21

Engineered drug-resistant immunocompetent cells enhance tumor cell killing during a chemotherapy challenge

Anindya Dasgupta, David McCarty, H. Trent Spencer

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 324 KB

english, 2010

22

Transplantation of hematopoietic stem cells encoding a high-expression factor VIII transgene under myeloablative and nonmyeloablative conditioning provides curative factor VIII activity to hemophilia A mice

Christopher B. Doering, Lucienne M. Ide, Bagirath Gangadharan, David McCarty, Elisabeth Javazon, H. Trent Spencer

Journal:

Blood Cells, Molecules, and Diseases

Year:

2008

Language:

english

File:

PDF, 69 KB

english, 2008

23

Erratum to “Response to 5-fluorouracil chemotherapy is modified by dietary folic acid deficiency in ApcMin/+ mice” [Cancer Lett. 187 (2002) 153–162]

Jody M. Tucker, Celestia Davis, Maria E. Kitchens, Marlene A. Bunni, David G. Priest, H.Trent Spencer, Franklin G. Berger

Journal:

Year:

2003

Language:

english

File:

PDF, 51 KB

english, 2003

24

Site-directed mutagenesis of a potential catalytic and formyl phosphate binding site and substrate inhibition of N10-formyltetrahydrofolate synthetase

Adam B Leaphart, H Trent Spencer, Charles R Lovell

Journal:

Archives of Biochemistry and Biophysics

Year:

2002

Language:

english

File:

PDF, 126 KB

english, 2002

25

Response to 5-fluorouracil chemotherapy is modified by dietary folic acid deficiency in ApcMin/+ mice

Jody M Tucker, Celestia Davis, Maria E Kitchens, Marlene A Bunni, David G Priest, H.Trent Spencer, Franklin G Berger

Journal:

Year:

2002

Language:

english

File:

PDF, 184 KB

english, 2002

26

Rapid Generation of Stable Cell Lines Expressing High Levels of Erythropoietin, Factor VIII, and an Antihuman CD20 Antibody Using Lentiviral Vectors

Baranyi, Lajos, Doering, Christopher B., Denning, Gabriella, Gautney, Richard E., Harris, Kyle T., Spencer, H. Trent, Roy, Andre, Zayed, Hatem, Dropulic, Boro

Journal:

Human Gene Therapy Methods

Year:

2013

Language:

english

File:

PDF, 1.19 MB

english, 2013

27

Substitution at Residue 214 of Human Thymidylate Synthase Alters Nucleotide Binding and Isomerization of Ligand−Protein Complexes †

Steadman, David J., Spencer, H. Trent, Dunlap, R. Bruce, Berger, Sondra H.

Journal:

Year:

1999

Language:

english

File:

PDF, 96 KB

english, 1999

28

Catalytic Cysteine of Thymidylate Synthase Is Activated upon Substrate Binding †,‡

Phan, Jason, Mahdavian, Elahe, Nivens, Michael C., Minor, Wladek, Berger, Sondra, Spencer, H. Trent, Dunlap, R. Bruce, Lebioda, Lukasz

Journal:

Year:

2000

Language:

english

File:

PDF, 323 KB

english, 2000

29

A Structural Role for Glutamine 214 in Human Thymidylate Synthase †

Steadman, David J., Zhao, Pei-Shan, Spencer, H. Trent, Dunlap, R. Bruce, Berger, Sondra H.

Journal:

Year:

1998

Language:

english

File:

PDF, 86 KB

english, 1998

30

Critical Role of Phenylalanine 34 of Human Dihydrofolate Reductase in Substrate and Inhibitor Binding and in Catalysis

Nakano, Takayuki, Spencer, H. Trent, Appleman, James R., Blakley, Raymond L.

Journal:

Year:

1994

Language:

english

File:

PDF, 1013 KB

english, 1994

31

Kinetic Scheme for Thymidylate Synthase from Escherichia coli : Determination from Measurements of Ligand Binding, Primary and Secondary Isotope Effects, and Pre-Steady-State Catalysis †

Spencer, H. Trent, Villafranca, J. Ernest, Appleman, James R.

Journal:

Year:

1997

Language:

english

File:

PDF, 463 KB

english, 1997

32

Retroviral Expression of Escherichia coli Thymidylate Synthase cDNA Confers High-Level Antifolate Resistance to Hematopoietic Cells

Shaw, David, Berger, Franklin G., Spencer, H. Trent

Journal:

Human Gene Therapy

Year:

2001

Language:

english

File:

PDF, 269 KB

english, 2001

33

Directed Engineering of a High-expression Chimeric Transgene as a Strategy for Gene Therapy of Hemophilia A

Doering, Christopher B, Denning, Gabriela, Dooriss, Kerry, Gangadharan, Bagirath, Johnston, Jennifer M, Kerstann, Keith W, McCarty, David A, Spencer, H Trent

Journal:

Molecular Therapy

Year:

2009

Language:

english

File:

PDF, 255 KB

english, 2009

34

Complete Regression of Large Solid Tumors Using Engineered Drug-Resistant Hematopoietic Cells and Anti-CD137 Immunotherapy

McMillin, Douglas W., Hewes, Becker, Gangadharan, Bagirath, Archer, David R., Mittler, Robert S., Spencer, H. Trent

Journal:

Human Gene Therapy

Year:

2006

Language:

english

File:

PDF, 1.30 MB

english, 2006

35

Simplified prototyping of perfusable polystyrene microfluidics

Tran, Reginald, Ahn, Byungwook, R. Myers, David, Qiu, Yongzhi, Sakurai, Yumiko, Moot, Robert, Mihevc, Emma, Trent Spencer, H., Doering, Christopher, A. Lam, Wilbur

Journal:

Biomicrofluidics

Year:

2014

Language:

english

File:

PDF, 2.09 MB

english, 2014

36

Comparison of Factor VIII Transgenes Bioengineered for Improved Expression in Gene Therapy of Hemophilia A

Dooriss, Kerry L., Denning, Gabriela, Gangadharan, Bagirath, Javazon, Elisabeth H., McCarty, David A., Spencer, H. Trent, Doering, Christopher B.

Journal:

Human Gene Therapy

Year:

2009

Language:

english

File:

PDF, 26.74 MB

english, 2009

37

Advancements in gene transfer-based therapy for hemophilia A

Doering, Christopher B, Spencer, H Trent

Journal:

Expert Review of Hematology

Year:

2009

Language:

english

File:

PDF, 391 KB

english, 2009

38

Lentiviral Vector Platform for Production of Bioengineered Recombinant Coagulation Factor VIII

Spencer, H Trent, Denning, Gabriela, Gautney, Richard E, Dropulic, Boro, Roy, Andre J, Baranyi, Lajos, Gangadharan, Bagirath, Parker, Ernest T, Lollar, Pete, Doering, Christopher B

Journal:

Molecular Therapy

Year:

2011

Language:

english

File:

PDF, 943 KB

english, 2011

39

Hematopoietic Stem Cells Encoding Porcine Factor VIII Induce Pro-coagulant Activity in Hemophilia A Mice with Pre-existing Factor VIII Immunity

Doering, Christopher B, Gangadharan, Bagirath, Dukart, Hillary Z, Spencer, H Trent

Journal:

Molecular Therapy

Year:

2007

Language:

english

File:

PDF, 236 KB

english, 2007

40

Improved Outcomes Following Drug-Resistant Immunotherapy in a Hunan Xenograft Model of Temozolomide-Resistant Glioblastoma Multiforme

Spencer, Harold Trent, Dasgupta, Anindya, Gillespie, George Yancey, Pereboeva, Larisa, Sutton, Kathryn S., Lamb, Lawrence

Journal:

Biology of Blood and Marrow Transplantation

Year:

2015

Language:

english

File:

PDF, 53 KB

english, 2015

41

Bioengineering and serum free expansion of blood-derived γδ T cells

Sutton, Kathryn S., Dasgupta, Anindya, McCarty, David, Doering, Christopher B., Spencer, H. Trent

Journal:

Year:

2016

Language:

english

File:

PDF, 1.55 MB

english, 2016

42

Canaliculitis caused by Citrobacter freundii

Rocke, John, Roydhouse, Trent, Spencer, Tarney

Journal:

Clinical & Experimental Ophthalmology

Year:

2016

Language:

english

File:

PDF, 316 KB

english, 2016

43

SPIE Proceedings [SPIE Enabling Technologies for Law Enforcement and Security - Boston, MA (Sunday 1 November 1998)] Enforcement and Security Technologies - Assessing the security vulnerabilities of correctional facilities

Spencer, Debra D., Morrison, G. Steve, DePersia, A. Trent, Pennella, John J.

Year:

1998

Language:

english

File:

PDF, 329 KB

english, 1998

44

Desmoid fibromatosis: MRI features of response to systemic therapy

Sheth, Pooja J., del Moral, Spencer, Wilky, Breelyn A., Trent, Jonathan C., Cohen, Jonathan, Rosenberg, Andrew E., Temple, H. Thomas, Subhawong, Ty K.

Journal:

Skeletal Radiology

Year:

2016

Language:

english

File:

PDF, 1.20 MB

english, 2016

45

Genetic engineering of chimeric antigen receptors using lamprey derived variable lymphocyte receptors

Moot, Robert, Raikar, Sunil S, Fleischer, Lauren, Querrey, Melissa, Tylawsky, Daniel E, Nakahara, Hirotomo, Doering, Christopher B, Spencer, H Trent

Journal:

Molecular Therapy — Oncolytics

Year:

2016

Language:

english

File:

PDF, 1.00 MB

english, 2016

46

456. Transgene Bioengineering Through Ancestral Protein Reconstruction

Zakas, Philip M., Brown, Harrison C., Knight, Kristopher A., Parker, Ernest T., Spencer, H. Trent, Gaucher, Eric A., Doering, Christopher B.

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 327 KB

english, 2016

47

207. Variable Lymphocyte Receptors Enable Development of Chimeric Antigen Receptors for the Treatment of T-Cell Malignancies

Raikar, Sunil S., Tylawsky, Daniel, Moot, Robert, Fleischer, Lauren, McCarty, David, Doering, Christopher, Spencer, H. Trent

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 1.91 MB

english, 2016

48

402. Bioengineering of Peripheral Blood Derived Gamma Delta T Cells in a Serum-Free Expansion Medium

Sutton, Kathryn, Dasgupta, Anindya, David, McCarty, Doering, Christopher, Spencer, H. Trent

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 330 KB

english, 2016

49

670. A Novel Approach to Expand Antigen Recognition in Chimeric Antigen Receptors

Moot, Robert, Raikar, Sunil, Fleischer, Lauren, Querrey, Melissa, Doering, Christopher, Spencer, Trent

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 365 KB

english, 2016

50

728. Tissue-Directed Transgene Engineering for AAV and Lentivector Gene Therapy Approaches

Brown, Harrison C., Zakas, Phillip M., George, Stephan N., Parker, Ernest T., Spencer, H. Trent, Doering, Christopher B.

Journal:

Molecular Therapy

Year:

2016

Language:

english

File:

PDF, 299 KB

english, 2016

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